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                當前位置:對照品 > 菌種購買 > 細胞 >
                慢性髓原白血病細胞K-562
                ??【編號】:K-562

                ??【產品名稱】:慢性髓原白血病細胞K-562

                ??【規格】:株

                ??【用途】:僅供研究之用

                  K-562人慢性髓原白血病細胞

                  描述:連續細胞株K-562由Lozzio從一位臨終的53歲女性慢性骨髓性白血病患者的胸水中建立。 細胞被歸入高度未分化的粒性白細胞類。 Anderson等對其表面膜性質的研究表明,K-562是一株人類紅白血病細胞。 K-562細胞株在自然殺傷分析中廣泛作為高敏感的體外受體。 See Pross等將它用于NK細胞的體外詳細檢測,包括NK細胞活性的數學量化。 K-562母細胞是多能性,造血惡性細胞,它能自發分化成可識別的紅血球祖細胞、粒性白細胞、單核細胞等。它是EBNA陰性的。
                  動物種別:人
                  性別:女
                  組織來源:骨髓;慢性骨髓性白血病(CML)
                  形態:淋巴母細胞
                  培養基和添加劑:IMDM培養基(GIBCO,貨號12200036),90%;優質胎牛血清,10%。 氣相:空氣,95%;二氧化碳,5%。 溫度:37攝氏度。
                  供應限制:A。僅供研究之用。
                  REFERENCE:Koeffler HP , Golde DW . Human myeloid leukemia cell lines: a review. Blood 56: 344-350, 1980. PubMed: 6996765 Ortaldo JR , et al. Specificity of natural cytotoxic reactivity of normal human lymphocytes against a myeloid leukemia cell line. J. Natl. Cancer Inst. 59: 77-82, 1977. PubMed: 69036 Lozzio CB , Lozzio BB . Human chronic myelogenous leukemia cell-line with positive Philadelphia chromosome. Blood 45: 321-334, 1975. PubMed: 163658 Lozzio BB , Lozzio CB . Properties and usefulness of the original K-562 human myelogenous leukemia cell line. Leuk. Res. 3: 363-370, 1979. PubMed: 95026 Andersson LC , et al. K562--a human erythroleukemic cell line. Int. J. Cancer 23: 143-147, 1979. PubMed: 367973 Lozzio BB , et al. A multipotential leukemia cell line (K-562) of human origin. Proc. Soc. Exp. Biol. Med. 166: 546-550, 1981. PubMed: 7194480 Dimery IW , et al. Variation amongst K562 cell cultures. Exp. Hematol. 11: 601-610, 1983. PubMed: 6576909 Chan YJ , et al. Two distinct upstream regulatory domains containing multicopy cellular transcription factor binding sites provide basal repression and inducible enhancer characteristics to the immediate-early IES (US3) promoter from human cytomegalovirus. J. Virol. 70: 5312-5328, 1996. PubMed: 8764042 Kolanus W , et al. alphaLbeta2 integrin/LFA-1 binding to ICAM-1 induced by cytohesin-1 a cytoplasmic regulatory molecule. Cell 86: 233-242, 1996. PubMed: 8706128 Gan W , Rhoads RE . Internal initiation of translation directed by the 5'-untranslated region of the mRNA for eIF4G, a factor involved in the picornavirus-induced switch from cap-dependent to internal initiation. J. Biol. Chem. 271: 623-626, 1996. PubMed: 8557663 Tiffany HL , et al. Enhanced expression of the eosinophil-derived neurotoin ribonuclease (RNS2) gene requires interaction between the promoter and intron. J. Biol. Chem. 271: 12387-12393, 1996. PubMed: 8647842 Chan YJ , et al. Synergistic interactions between overlapping binding sites for the serum response factor and ELK-1 proteins mediate both basal enhancement and phorbol ester responsiveness of primate cytomegalovirus. J. Virol. 70: 8590-8605, 1996. PubMed: 8970984 Nauseel WM , et al. Effect of the R569W missense mutation on the biosynthesis of myeloperoxidase. J. Biol. Chem. 271: 9546-9549, 1996. PubMed: 8621627 Grune T , et al. Degradation of oxidized proteins in K562 human hematopoietic cells by proteasome. J. Biol. Chem. 271: 15504-15509, 1996. PubMed: 8663134 Jondal M , Pross H . Surface markers on human b and t lymphocytes. VI. Cytotoxicity against cell lines as a functional marker for lymphocyte subpopulations. Int. J. Cancer 15: 596-605, 1975. PubMed: 806545 West WH , et al. Natural cytotoxic reactivity of human lymphocytes against a myeloid cell line: characterization of effector cells. J. Immunol. 118: 355-361, 1977. PubMed: 299761 Pross HF , et al. Spontaneous human lymphocyte-mediated cytotoxicity against tumor target cells. IX. The quantitation of natural killer cell activity. J.www.atcc360.com Clin. Immunol. 1: 51-63, 1981. PubMed: 7334070 Chen TR . Modal karyotype of human leukemia cell line, K562 (ATCC CCL 243). Cancer Genet. Cytogenet. 17: 55-60, 1985. PubMed: 3857109 Wu SQ , et al. Extensive amplification of bcr/abl fusion genes clustered on three marker chromosomes in human leukemic cell line K-56. Leukemia 9: 858-862, 1995.
                  中文名稱:人慢性髓原白血病細胞
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